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For females, sexual dysfunction could suggest problems with sexual arousal, problem attaining orgasm, or discomfort throughout sex-related intercourse. For some people, taking Amitriptyline can lead to sex-related dysfunction. Dealing with sexual disorder caused by Amitriptyline can be tough. Amitriptyline is not the only medication that can create sexual disorder. If you’re taking Amitriptyline and also experiencing sexual disorder, don’t be reluctant to seek help.